Looping anomalies


Isolated dextrocardia

Normal circulation in the body is characterized by the continual reoxygenation of blood in the lungs and the circulation of oxygenated blood throughout the body.

In isolated dextrocardia, only outflow trunks are transposed. Venous system and other organs are normal. Characterized by two independent blood circulations: (1) an oxygenated circuit LA-LV-Lung, and (2) a deoxygenated circuit RA-RV-Body.

Cases are characterized by cyanosis, due to deoxygenated blood in the systemic circulation. Since normal hemodynamics are usually not established in isolated dextrocardias, the internal structures and septae usually have abnormal formation. These defects allow some mixing of blood between the two circuits. This affords some survival value.

Situs inversus (totalis)

This is dextrocardia, with all structures inverted (chambers and outflow trunks), so as to give an entirely normal function.

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