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Valvular atresias arise from the uneven partition of the AV canal. Depending on the size and position of the narrowed channel, a tricuspid atresia or a biscuspid atresia results. Atresias arising from anomalous partition of the canal are referred to as congenital atresias.
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As the partition of the AV canal affects the blood flow through the primitive ventricle, any changes in blood flow can adversely affect bulboventricular looping. Valvular atresias can also be acquired (after rheumatic fever, which is a complication of untreated group A streptococcal infection).
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