Normal development


Normal embryonic development of the cardiovascular system involves the transition from a primitive single-chambered tube into a highly specialized, 4-chambered heart.

Each set of events is arranged as a tutorial. it is suggested that each tutorial be followed in the order presented, as later topics are based upon and build from earlier material.

The following discussions follow a logical progression. It is strongly recommended to follow the prompts at the end of each section.

Tutorial 1: Early Events

Establishment of basic cell populations and architecture upon which further changes occur.

Tutorial 2: Critical Changes

Internal changes which model the heart tube into the 4-chambered adult configuration.

Tutorial 3: Vascular Changes

These changes transform the symmetric embryonic vasculature into the asymmetrical adult configuration.