Endocrinology

Progesterone and, to a lesser extent, estrogen are produced by the corpus luteum. The corpus luteum evolves under the influence of the pre-ovulatory surge in LH. LH and FSH are under negative feedback control by these ovarian hormones at the level of the pituitary gland.

 Follicular Development

After ovulation, mural granulosa cells and thecal cells of the dominant follicle remain in the ovary and become the corpus luteum.

 Uterine Endometrial Cycle

Progesterone stimulates endometrial glands to secrete glycogen, mucus, and other substances. The endometrial glands now have a tortuous appearance.