CDC Area of Risk – Risk in all rural areas at altitudes <800m (<2,624ft). No risk in Bogotá and vicinity.
Chloroquine Resistance – Confirmed.
Recommended Prophylaxis – Atovaquone/ proguanil; doxycycline; or mefloquine.

WHO Malaria risk—P. falciparum (38%), P. vivax (62%)—is high throughout the year in rural/jungle areas below 800 m, especially in municipalities of the regions of Amazonia, Orinoquía, Pacífico and Urabá-Bajo Cauca. Transmission intensity varies by department, with the highest risk in Amazonas, Chocó, Córdoba, Guainía, Guaviare, Putumayo and the departments of Amazonas, Caquetá, Chocó Córdoba, Guainía, Guaviare, Meta, Nariño, Valle del Cauca, Vaupés and Vichada. Chloroquine-resistant P. falciparum exists in Amazonia, Pacífico and Urabá-Bajo Cauca. Resistance to sulfadoxine–pyrimethamine reported.
Recommended prevention in risk areas: III; in Amazonia, Pacífico and Urabá-Bajo Cauca, IV.

 
CDC Country requirements: Vaccination not required.
CDC recommendations: Vaccination recommended for all travelers >9 months of age. Travelers whose itinerary is limited to the cities of Bogotá, Cali, or Medellín are at lower risk and may consider foregoing vaccination.

WHO Vaccination is recommended for travellers who may visit the following areas considered to be endemic for yellow fever: middle valley of the Magdalena river, eastern and western foothills of the Cordillera Oriental from the frontier with Ecuador to that with Venezuela, Urabá, foothills of the Sierra Nevada, eastern plains (Orinoquia) and Amazonia.